The role of scavenger receptors in pathogen recognition and innate immunity

Immunobiology. 2004;209(1-2):39-49. doi: 10.1016/j.imbio.2004.02.004.

Abstract

Scavenger receptors represent a large family of structurally unrelated distinct gene products, expressed by myeloid and selected endothelial cells and able to recognise modified low-density lipoproteins. They also bind and internalise a variety of microbial pathogens, as well as modified or endogenous molecules derived from the host, and contribute to a range of physiological or pathological processes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antigen Presentation
  • Bacteria / pathogenicity
  • Fungi / pathogenicity
  • Immunity, Innate*
  • Ligands
  • Parasites / pathogenicity
  • Receptors, Immunologic / immunology
  • Receptors, Immunologic / physiology*
  • Receptors, Scavenger
  • Viruses / pathogenicity

Substances

  • Ligands
  • Receptors, Immunologic
  • Receptors, Scavenger