Metathesis approach to the synthesis of polyheterocyclic structures from oxanorbornenes

Jeffrey D Winkler; Sylvie M Asselin; Stacey Shepard; Jing Yuan

doi:10.1021/ol0484106

Metathesis approach to the synthesis of polyheterocyclic structures from oxanorbornenes

Org Lett. 2004 Oct 14;6(21):3821-4. doi: 10.1021/ol0484106.

Authors

Jeffrey D Winkler¹, Sylvie M Asselin, Stacey Shepard, Jing Yuan

Affiliation

¹ Department of Chemistry, University of Pennsylvania Philadelphia, Pennsylvania 19104, USA. winkler@sas.upenn.edu

PMID: 15469358
DOI: 10.1021/ol0484106

Abstract

[reaction: see text] The synthesis of stereochemically defined tri- and penta-heterocyclic ring systems 9 and 28, respectively, via the metathesis reaction of substituted oxanorbornanes derived from 3 is described.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Heterocyclic Compounds / chemical synthesis*
Molecular Structure
Norbornanes / chemistry*

Substances

Heterocyclic Compounds
Norbornanes

Grants and funding

CA40250/CA/NCI NIH HHS/United States