Anatomy based inverse planning in HDR prostate brachytherapy

Inger-Karine K Kolkman-Deurloo; Xavier G J Deleye; Peter P Jansen; Peter C M Koper

doi:10.1016/j.radonc.2004.08.014

Anatomy based inverse planning in HDR prostate brachytherapy

Radiother Oncol. 2004 Oct;73(1):73-7. doi: 10.1016/j.radonc.2004.08.014.

Authors

Inger-Karine K Kolkman-Deurloo¹, Xavier G J Deleye, Peter P Jansen, Peter C M Koper

Affiliation

¹ Department of Radiation Oncology, Erasmus MC-Daniel Den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA Rotterdam, The Netherlands.

PMID: 15465149
DOI: 10.1016/j.radonc.2004.08.014

Abstract

The purpose of this study is to evaluate anatomy based inverse planning as implemented in PLATO BPS 14.2 for planning of HDR prostate implants. Six patients were analysed. The dose distributions were optimized using geometric optimization followed by graphical optimization (GO), anatomy based inverse planning or standard inverse optimization (SIO), tuned inverse optimization (TIO) and tuned inverse optimization followed by graphical optimization (GOTIO). The mean target coverage was 93+/-4%, 53+/-11%, 74+/-8%, 90+/-3%, respectively, for GO, SIO, TIO and GOTIO. The conformal index COIN was 0.74+/-0.02, 0.43+/-0.15 and 0.77+/-0.07, respectively, for GO, SIO and GOTIO. Improved dose homogeneity was found when comparing GOTIO with GO.

MeSH terms

Brachytherapy / methods*
Humans
Male
Prostate / anatomy & histology
Prostatic Neoplasms / radiotherapy*
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted