Reduction in neutrophil elastase concentration by recombinant alphal-antitrypsin (recAAT) does not alter bacterial loading in the sputum of cystic fibrosis patients

Br J Biomed Sci. 2004;61(3):146-7. doi: 10.1080/09674845.2004.11732661.

Authors

J E Moore¹, A Shaw, B C Millar, S L Martin, P G Murphy, D G Downey, M Ennis, J S Elborn

Affiliation

¹ Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Northern Ireland, UK. jemoore@niphl.dnet.co.uk

PMID: 15462261
DOI: 10.1080/09674845.2004.11732661

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Bacterial Infections / complications
Bacterial Infections / drug therapy
Colony Count, Microbial / methods
Cystic Fibrosis / complications
Cystic Fibrosis / drug therapy
Cystic Fibrosis / microbiology*
Humans
Leukocyte Elastase / analysis*
Male
Middle Aged
Neutrophils / enzymology
Recombinant Proteins / therapeutic use
Serine Proteinase Inhibitors / therapeutic use*
Sputum / microbiology*
alpha 1-Antitrypsin / therapeutic use*

Substances

Recombinant Proteins
Serine Proteinase Inhibitors
alpha 1-Antitrypsin
Leukocyte Elastase