Visual estimation of the global myocardial extent of hyperenhancement on delayed contrast-enhanced MRI

Eur Radiol. 2004 Dec;14(12):2182-7. doi: 10.1007/s00330-004-2483-1. Epub 2004 Sep 28.

Abstract

MRI with paramagnetic contrast agent allows the assessment of the extent of myocardial tissue injury after infarction. Visual segmental scoring has been widely used to define the transmural extent of myocardial infarction, but no attempt has been made to use visual scores in order to assess the percentage of the whole myocardium infarcted. By summing all the segmental scores using a 17-segment model, a global index of the size of the infarcted myocardium is easily obtained. The entire left ventricle of 60 patients with a recent myocardial infarction was scanned using an ECG-gated gradient echo sequence after injection of gadolinium contrast agent. The global score was defined as the sum of the scores on each segment, and expressed as a percentage of the maximum possible score. This index was compared with a planimetric evaluation of hyperenhancement, expressed as a percentage of the left ventricle myocardial volume. There is a good correlation between the two methods (r=0.91; y=1.06x+0.20), and the Bland-Altman plot shows a high concordance between the two approaches (mean of the differences =1.45%). A visual approach based on a 17-segment model can be used to evaluate the global myocardial extent of the hyperenhancement with similar results to planimetry.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Contrast Media*
  • Echo-Planar Imaging*
  • Female
  • Gadolinium DTPA*
  • Humans
  • Image Enhancement*
  • Male
  • Middle Aged
  • Myocardial Infarction / complications
  • Myocardial Infarction / pathology*
  • Myocardium / pathology*
  • Observer Variation
  • Reproducibility of Results

Substances

  • Contrast Media
  • Gadolinium DTPA