An emerging role for Krüppel-like factors in vascular biology

Trends Cardiovasc Med. 2004 Aug;14(6):241-6. doi: 10.1016/j.tcm.2004.06.005.

Abstract

The Krüppel-like family of transcription factors play diverse roles regulating cellular differentiation and tissue development. Accumulating evidence supports an important role for these factors in vascular biology. This review examines the current knowledge of this gene family's role in key cell types that critically regulate vessel biology under physiologic and pathologic states.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • DNA-Binding Proteins*
  • Endothelium, Vascular / cytology
  • Humans
  • Kruppel-Like Transcription Factors
  • Monocytes
  • Repressor Proteins*
  • T-Lymphocytes
  • Transcription Factors*

Substances

  • DNA-Binding Proteins
  • Kruppel-Like Transcription Factors
  • Repressor Proteins
  • Transcription Factors