Isolation and characterization of five new tetrasaccharide glycosides from the roots of Ipomoea stans and their cytotoxic activity

J Nat Prod. 2004 Sep;67(9):1552-6. doi: 10.1021/np0400454.

Abstract

Five new tetrasaccharide glycosides, stansins 1-5, were isolated from the roots of Ipomoea stans, and their structures were elucidated using spectroscopic and chemical methods. Preliminary testing showed the cytotoxicity of 5 toward the OVCAR and UISO-SQC-1 cancer cell lines.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification*
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Drug Screening Assays, Antitumor
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Humans
  • Ipomoea / chemistry*
  • Mexico
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Roots / chemistry
  • Plants, Medicinal / chemistry*
  • Polysaccharides / chemistry
  • Polysaccharides / isolation & purification
  • Polysaccharides / pharmacology
  • Structure-Activity Relationship
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents, Phytogenic
  • Glycosides
  • Polysaccharides