Comparison of endothelial function in young men and women with a family history of premature coronary artery disease

Naomi M Hamburg; François Charbonneau; Marie Gerhard-Herman; Peter Ganz; Mark A Creager

doi:10.1016/j.amjcard.2004.05.067

Comparison of endothelial function in young men and women with a family history of premature coronary artery disease

Am J Cardiol. 2004 Sep 15;94(6):783-5. doi: 10.1016/j.amjcard.2004.05.067.

Authors

Naomi M Hamburg¹, François Charbonneau, Marie Gerhard-Herman, Peter Ganz, Mark A Creager

Affiliation

¹ Evans Department of Medicine and Whitaker Cardiovascular Institute, Boston University School of Medicine, 75 Francis Street, Boston, MA 02115, USA.

PMID: 15374789
DOI: 10.1016/j.amjcard.2004.05.067

Abstract

Endothelial function was evaluated in 34 young men and women with a family history of premature coronary artery disease (CAD) and 28 control subjects. Men with a family history of CAD had significantly impaired flow-mediated, endothelium-dependent vasodilation of the brachial artery compared with controls; however, in women, there was no difference in flow-mediated vasodilation between subjects with a family history and controls.

Publication types

Comparative Study
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Adult
Brachial Artery / diagnostic imaging
Brachial Artery / physiopathology
Case-Control Studies
Coronary Disease / genetics*
Coronary Disease / physiopathology*
Endothelium, Vascular / diagnostic imaging
Endothelium, Vascular / physiopathology*
Female
Humans
Male
Multivariate Analysis
Sex Factors
Ultrasonography
Vasodilation

Abstract

Publication types

MeSH terms

Grants and funding