[Water-soluble chemical constituents of Swertia davidi Franch]

Yao Xue Xue Bao. 2004 May;39(5):351-3.
[Article in Chinese]

Abstract

Aim: To study the active constituents of Swertia davidi Franch.

Methods: Column chromatographies on silica gel, Sephadex LH-20 and Diaion-201 et al. were used to isolate and purify the chemical components. Their structures were identified by UV, IR, MS, NMR and 2D-NMR.

Results: These compounds were elucidated as 8-O-beta-D-glucopyranosyl-1, 3, 5-trihydroxyxanthone (I), 5-O-beta-D-glucopyranosyl-1, 8-dihydroxy-3-methoxyxanthone (II), 5-O-beta-D-glucopyranosyl-1, 3, 8-trihydroxyxanthone (III) and swertamarin (IV).

Conclusion: Compound III is a new xanthone glucoside. The other compounds were isolated from this plant for the first time.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Glucosides / chemistry
  • Glucosides / isolation & purification*
  • Molecular Conformation
  • Molecular Structure
  • Plants, Medicinal / chemistry*
  • Swertia / chemistry*
  • Xanthones / chemistry
  • Xanthones / isolation & purification*

Substances

  • 5-O-glucopyranosyl-1,3,8-trihydroxyxanthone
  • Glucosides
  • Xanthones
  • norswertianolin