Aerosolized iloprost as a bridge to lung transplantation in a patient with cystic fibrosis and pulmonary hypertension

Ann Thorac Surg. 2004 Sep;78(3):e48-50. doi: 10.1016/j.athoracsur.2003.12.096.

Abstract

We describe a patient with cystic fibrosis, end-stage lung disease, and secondary pulmonary hypertension in whom aerosolized iloprost was effective in lowering pulmonary artery pressure and improving functional status, thus proving successful as a bridge to lung transplantation. Inhaled iloprost may be an efficient and selective approach to treat pulmonary hypertension related to end-stage obstructive pulmonary disease.

Publication types

  • Case Reports

MeSH terms

  • Administration, Inhalation
  • Adult
  • Cystic Fibrosis / complications*
  • Female
  • Humans
  • Hypertension, Pulmonary / complications*
  • Hypertension, Pulmonary / drug therapy
  • Iloprost / administration & dosage*
  • Lung Transplantation / methods*
  • Nitric Oxide / administration & dosage
  • Premedication*
  • Respiratory Insufficiency / etiology
  • Respiratory Insufficiency / surgery*
  • Vascular Resistance / drug effects
  • Vasodilator Agents / administration & dosage*

Substances

  • Vasodilator Agents
  • Nitric Oxide
  • Iloprost