Abstract
A new alpha-glucosidase inhibitor, penasulfate A, has been isolated from a marine sponge Penares sp.(1) Its structure was elucidated by spectral and chemical methods to be a scalemic mixture of methyl pipecolates acylated with a novel sulfated fatty acid.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Enzyme Inhibitors / chemistry
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Enzyme Inhibitors / isolation & purification*
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Enzyme Inhibitors / pharmacology
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Fatty Acids / chemistry
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Fatty Acids / isolation & purification*
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Fatty Acids / pharmacology
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Glycoside Hydrolase Inhibitors*
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Hypoglycemic Agents / chemistry
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Hypoglycemic Agents / isolation & purification*
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Hypoglycemic Agents / pharmacology
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Japan
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Pipecolic Acids / chemistry
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Pipecolic Acids / isolation & purification*
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Pipecolic Acids / pharmacology
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Porifera / chemistry*
Substances
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Enzyme Inhibitors
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Fatty Acids
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Glycoside Hydrolase Inhibitors
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Hypoglycemic Agents
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Pipecolic Acids
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penasulfate A