An increase in the mycotic infections has been observed in recent decades. It is the effect of the development of industry, large migrations, living in huge aglomerations, usage of the public swimming-pools, wearing impervious clothes and shoes. Systemic diseases: diabetes, obesity, hormonal disorders, immune and food deficiency, AIDS, neoplasms and prescription drugs: antibiotics, corticosteroids and immunosuppressants, cause mycoses. Mycoses belong to chronic diseases, they are difficult to treat and very often recur. A lot of antimycotic drugs are known, but the most effective are azoles and alliloamines. An intensive research is conducted on introduction of new and more effective and cheaper preparations.