Seoul hantavirus in Europe: first demonstration of the virus genome in wild Rattus norvegicus captured in France

Eur J Clin Microbiol Infect Dis. 2004 Sep;23(9):711-7. doi: 10.1007/s10096-004-1196-3. Epub 2004 Aug 18.

Abstract

Although rats (Rattus rattus or Rattus norvegicus) worldwide have been found to carry Seoul hantavirus, there are at present only a very few reports of confirmed human Seoul hantavirus infections outside Asia, where the virus, in certain areas, is responsible for approximately 25% of the human hantavirus infections. In Europe, no confirmed human infections outside laboratories have been described, and although rats occasionally have been found to be antibody positive, the viral genome has not been demonstrated in these animals. The present report describes the first confirmed finding of Seoul hantavirus in R. norvegicus captured in Europe.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Wild
  • Antibodies, Viral / analysis
  • Base Sequence
  • DNA, Viral / analysis
  • Europe / epidemiology
  • Fluorescent Antibody Technique, Indirect
  • Genome
  • Hantavirus Infections / epidemiology
  • Hantavirus Infections / virology*
  • Immunoenzyme Techniques
  • Molecular Sequence Data
  • Orthohantavirus / classification
  • Orthohantavirus / genetics*
  • Rats
  • Reverse Transcriptase Polymerase Chain Reaction / methods*
  • Rodent Diseases / epidemiology
  • Rodent Diseases / virology*
  • Sensitivity and Specificity

Substances

  • Antibodies, Viral
  • DNA, Viral