Neutron fibres and possible applications to NCT

Appl Radiat Isot. 2004 Nov;61(5):841-4. doi: 10.1016/j.apradiso.2004.05.039.

Abstract

We summarize previous researches regarding neutron guides of small transverse cross-section (neutron fibres), smaller than those of the standard hollow guides and collimators employed currently. Those studies may not be widely known in the neutron capture therapy (NCT) community, but they may be interesting for it. Such neutron fibres could allow to deliver and concentrate neutron beams selectively in regions of size smaller than 1mm. We present new estimates and point out and discuss some new possible specific applications of those neutron fibres, which would not replace standard NCT but could supplement it. Thus, we entertain the possibility that neutron fibres could be useful for additional therapies (in typical NCT durations) of: (i) rather small tumours, (ii) thin borders of tumours. The use of these neutron fibres could reduce the undesirable delivery of radiation to healthy tissue around regions with malignant tissue.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Boron Neutron Capture Therapy / instrumentation
  • Fast Neutrons / therapeutic use
  • Glass
  • Humans
  • Neoplasms / radiotherapy
  • Neutron Capture Therapy / instrumentation*