Novel coordinating motifs for lanthanide(III) ions based on 5-(2-pyridyl)tetrazole and 5-(2-pyridyl-1-oxide)tetrazole. Potential new contrast agents

Antonio Facchetti; Alessandro Abbotto; Luca Beverina; Silvia Bradamante; Palma Mariani; Charlotte L Stern; Tobin J Marks; Alberto Vacca; Giorgio A Pagani

doi:10.1039/b401919a

Novel coordinating motifs for lanthanide(III) ions based on 5-(2-pyridyl)tetrazole and 5-(2-pyridyl-1-oxide)tetrazole. Potential new contrast agents

Chem Commun (Camb). 2004 Aug 7:(15):1770-1. doi: 10.1039/b401919a. Epub 2004 Jun 30.

Authors

Antonio Facchetti¹, Alessandro Abbotto, Luca Beverina, Silvia Bradamante, Palma Mariani, Charlotte L Stern, Tobin J Marks, Alberto Vacca, Giorgio A Pagani

Affiliation

¹ Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.

PMID: 15278178
DOI: 10.1039/b401919a

Abstract

Water-soluble and neutral Ln(III) and Zn (II) complexes of pyridine- and (pyridine-1-oxide)tetrazole have been synthesized and the Gd derivatives have great potential as high-relaxivity low-osmolarity MRI contrast agents.