Dydrogesterone-induced hepatitis and autoimmune hemolytic anemia

Turk J Gastroenterol. 2004 Mar;15(1):49-52.

Abstract

Dydrogesterone, similar to women's natural progesterone, has been used in a wide range of gynecological conditions. Despite its widespread use, dydrogesterone-induced hepatotoxicity and dydrogesterone-induced hemolytic anemia have, to the best of our knowledge, never been reported previously. We describe a case of hepatitis and warm antibody hemolytic anemia due to dydrogesterone.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Anemia, Hemolytic, Autoimmune / chemically induced*
  • Anemia, Hemolytic, Autoimmune / therapy
  • Biopsy, Needle
  • Chemical and Drug Induced Liver Injury / etiology*
  • Chemical and Drug Induced Liver Injury / therapy
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Dydrogesterone / adverse effects*
  • Dydrogesterone / therapeutic use
  • Female
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Liver Function Tests
  • Risk Assessment
  • Severity of Illness Index

Substances

  • Dydrogesterone