(-)-(3S)-4-(2-{[4,4-Dimethoxy-6-(benzyloxymethyl)perhydropyran-2-yl]methyl}-1,3-dithian-2-yl)-4-methyl-3-(1,1,2,2-tetramethyl-1-silapropoxy)pentan-1-ol

Hiroyuki Hosomi; Shigeru Ohba; Ken Ohmori; Tetsuo Obitsu; Yasuyuki Ogawa; Yuichi Ishikawa; Shosuke Yamamura; Shigeru Nishiyama

doi:10.1107/S010827010000336X

(-)-(3S)-4-(2-{[4,4-Dimethoxy-6-(benzyloxymethyl)perhydropyran-2-yl]methyl}-1,3-dithian-2-yl)-4-methyl-3-(1,1,2,2-tetramethyl-1-silapropoxy)pentan-1-ol

Acta Crystallogr C. 2000 Apr 15;56(Pt 4):E140-E141. doi: 10.1107/S010827010000336X. Epub 2000 Apr 15.

Authors

Hiroyuki Hosomi¹, Shigeru Ohba, Ken Ohmori, Tetsuo Obitsu, Yasuyuki Ogawa, Yuichi Ishikawa, Shosuke Yamamura, Shigeru Nishiyama

Affiliation

¹ Department of Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi 3-14-1, Kohoku-ku, Yokohama 223-8522, Japan.

PMID: 15263181
DOI: 10.1107/S010827010000336X

Abstract

The absolute configuration was determined for the title compound, (-)-C(32)H(56)O(6)S(2)Si, (I), which was prepared in a synthetic study on the natural products bryostatins. Two independent molecules show similar conformations, except for the orientation of the methoxy groups.