Prevalence of pregnancy related oral granuloma in a Nigerian population group and the possible role of contraceptives

Afr J Med Med Sci. 2003 Dec;32(4):409-12.

Abstract

A clinicopathological survey on pregnancy related tumours was carried out on 400 randomly selected pregnant Nigerian women. Fifteen (15) cases of pregnancy granuloma or 'epulis gravidanum' were found. Of these subjects, 287 representing 71.8 percent were on birth control before conception, while 113 or 28.2 percent were not. Nine (9) cases of pregnancy tumour were found in the group on birth control pills and six (6) in the group not on birth control representing an incidence of 3.1 and 5.3 percent respectively. Literature review indicate a general incidence of between 0-2.5 percent. Five of the granuloma regressed post partum, while ten were excised. Patients were followed 1-2 years post partum and no recurrence was recorded, even in patients who have re-commenced on contraceptives.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Contraceptives, Oral, Hormonal / adverse effects
  • Female
  • Granuloma, Pyogenic / chemically induced
  • Granuloma, Pyogenic / epidemiology*
  • Granuloma, Pyogenic / physiopathology
  • Humans
  • Middle Aged
  • Mouth Diseases / chemically induced
  • Mouth Diseases / epidemiology*
  • Mouth Diseases / physiopathology
  • Nigeria / epidemiology
  • Oral Hygiene Index
  • Pregnancy
  • Pregnancy Complications / chemically induced
  • Pregnancy Complications / epidemiology*
  • Pregnancy Complications / physiopathology
  • Prevalence

Substances

  • Contraceptives, Oral, Hormonal