Markedly asymmetrical parkinsonism as a leading feature of adult-onset Huntington's disease

Mov Disord. 2004 Jul;19(7):854-856. doi: 10.1002/mds.20093.

Abstract

We report on a 28-year-old man who presented with right hand tremor, bradykinesia, and rigidity of his right side extremities. Our case report emphasizes that markedly asymmetrical parkinsonism can be an initial presentation of adult-onset Huntington's disease (HD), and different clinical presentations can be observed in members of an individual HD family with the same CAG repeat length.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alleles
  • Antiparkinson Agents / therapeutic use
  • Carbidopa / therapeutic use
  • Cognition Disorders / diagnosis
  • Cognition Disorders / etiology
  • Diagnosis, Differential
  • Drug Combinations
  • Humans
  • Huntington Disease / complications
  • Huntington Disease / diagnosis*
  • Huntington Disease / genetics*
  • Levodopa / therapeutic use
  • Male
  • Neuropsychological Tests
  • Parkinsonian Disorders / diagnosis*
  • Parkinsonian Disorders / drug therapy
  • Pedigree
  • Severity of Illness Index

Substances

  • Antiparkinson Agents
  • Drug Combinations
  • carbidopa, levodopa drug combination
  • Levodopa
  • Carbidopa