This study assesses similarities and differences in anti-smoking socialization beliefs of White and Native American parents in a low-income, rural population in northeastern Oklahoma. Data are from a population-based, cross-sectional children's environmental health study in which in-home interviews were conducted with 356 parents (56.2% White, 43.8% Native American), primarily mothers, of young children. Approximately 65% of the participants had a high school education or less and over 50% smoked. The Native American participants represented numerous tribes and did not live on reservations. Multivariate logistic regression models were used to examine associations between race/ethnicity, education, smoking status and six anti-smoking socialization beliefs. Results showed that White and Native American parents in this study were very similar in their anti-smoking socialization beliefs, with the one exception that Native American parents were less likely to believe that schools are better than parents in teaching children about the dangers of cigarette smoking. Parental education was significantly associated with the beliefs that all children will try smoking and that forbidding children to smoke will only make them want to smoke more, with less-educated parents more likely to share these beliefs. Findings suggest that interventions to promote anti-smoking socialization beliefs among parents with high school education or less may be important in low-income, rural communities with high smoking rates.