Development of a rubella vaccination strategy: contribution of a rubella susceptibility study of women of childbearing age in Kyrgyzstan, 2001

Clin Infect Dis. 2004 Jun 15;38(12):1780-3. doi: 10.1086/421018. Epub 2004 May 17.

Abstract

To contribute to the development of a rubella vaccination strategy, we conducted a study to determine age-specific susceptibility among women aged 15-39 years by testing for rubella-specific IgG antibodies. Of 964 women, 13% were found to be susceptible to rubella. Significantly higher susceptibility among women >25 years old was observed. Susceptibility data are important but are not sufficient to develop a vaccination strategy. After considering all available information, we suggested vaccination of women aged <35 years and selective vaccination of older women who were planning pregnancy.

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Viral / blood
  • Female
  • Humans
  • Immunity, Active
  • Kyrgyzstan
  • Rubella / immunology*
  • Rubella / prevention & control*
  • Rubella Vaccine / administration & dosage*
  • Rubella virus / immunology
  • Vaccination / standards

Substances

  • Antibodies, Viral
  • Rubella Vaccine