Effect of highly active antiretroviral therapy on cardiovascular involvement in children with human immunodeficiency virus infection

Pediatr Infect Dis J. 2004 Jun;23(6):559-63. doi: 10.1097/01.inf.0000130073.48745.a6.

Abstract

The impact of highly active antiretroviral therapy (HAART) on cardiovascular involvement was evaluated in 38 vertically human immunodeficiency virus-infected children followed up for 5 years. This study demonstrates for the first time in a cohort of children the resolution of previous dilated cardiomyopathy after the start of HAART and the absence of cardiovascular events related to metabolic abnormalities during the period of its administration.

Publication types

  • Comparative Study

MeSH terms

  • Age Distribution
  • Analysis of Variance
  • Antiretroviral Therapy, Highly Active / adverse effects*
  • Antiretroviral Therapy, Highly Active / methods
  • Cardiovascular Diseases / chemically induced*
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / epidemiology
  • Child
  • Child, Preschool
  • Cohort Studies
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Echocardiography
  • Electrocardiography
  • Female
  • HIV Infections / congenital
  • HIV Infections / drug therapy*
  • Humans
  • Incidence
  • Italy / epidemiology
  • Longitudinal Studies
  • Male
  • Probability
  • Prognosis
  • Risk Assessment
  • Severity of Illness Index
  • Sex Distribution