[Prostate stem cell antigen and related cancers]

Zhonghua Nan Ke Xue. 2004 May;10(5):382-4.
[Article in Chinese]

Abstract

Prostate stem cell antigen (PSCA) is a cell surface antigen expressed in normal prostate and overexpressed in cancers associated with prostate, bladder and pancreas. The sensitivity of PSCA labeling is higher than PSA in prostate cancer. PSCA can be used in the preparation of protein vaccine and nucleic acid vaccine. Further studies are required to confirm its safety and efficacy as a diagnostic means.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Antigens, Neoplasm
  • GPI-Linked Proteins
  • Humans
  • Immunotherapy
  • Male
  • Membrane Glycoproteins / analysis*
  • Membrane Glycoproteins / genetics
  • Membrane Glycoproteins / immunology
  • Neoplasm Proteins / analysis*
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / immunology
  • Pancreatic Neoplasms / diagnosis*
  • Prostatic Neoplasms / diagnosis*
  • Urinary Bladder Neoplasms / diagnosis*

Substances

  • Antigens, Neoplasm
  • GPI-Linked Proteins
  • Membrane Glycoproteins
  • Neoplasm Proteins
  • PSCA protein, human