[Effect of para-aminobenzonic acid (PABA) on cell-surface hydrophobicity of Streptococcus mutans]

Hua Xi Kou Qiang Yi Xue Za Zhi. 2004 Apr;22(2):149-51.
[Article in Chinese]

Abstract

Objective: To study the effect of Para-aminobenzonic acid on cell-surface hydrophobicity of Streptococcus mutans.

Methods: Microbial adhesion to hydrocarbons (MATH) was used to measure the cell-surface hydrophobicity of Streptococcus mutans which grew in modified Carlsson medium with different dilutions of PABA.

Results: The cell-surface hydrophobicity of Streptococcus mutans increased when Carlsson medium contained low dilution of PABA. But following the increase of PABA, the cell-surface hydrophobicity decreased.

Conclusion: Para-aminobenzonic acid could inhibit the adherence of Streptococcus mutans through changing its cell-surface hydrophobicity.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 4-Aminobenzoic Acid / pharmacology*
  • Bacterial Adhesion / drug effects*
  • Humans
  • Hydrophobic and Hydrophilic Interactions*
  • Streptococcus mutans / drug effects
  • Streptococcus mutans / physiology*

Substances

  • 4-Aminobenzoic Acid