Digital signal processor-based real-time optical Doppler tomography system

J Biomed Opt. 2004 May-Jun;9(3):454-63. doi: 10.1117/1.1695409.

Abstract

We present a real-time data-processing and display unit based on a custom-designed digital signal processor (DSP) module for imaging tissue structure and Doppler blood flow. The DSP module is incorporated into a conventional optical coherence tomography system. We also demonstrate the flexibility of embedding advanced Doppler processing algorithms in the DSP module. Two advanced velocity estimation algorithms previously introduced by us are incorporated in this DSP module. Experiments on Intralipid flow demonstrate that a pulsatile flow of several hundred pulses per minute can be faithfully captured in M-scan mode by this DSP system. In vivo imaging of a rat's abdominal blood flow is also presented.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, U.S. Gov't, P.H.S.
  • Validation Study

MeSH terms

  • Abdomen / blood supply*
  • Abdomen / physiology*
  • Algorithms*
  • Animals
  • Blood Flow Velocity / physiology
  • Equipment Design
  • Equipment Failure Analysis
  • Image Enhancement / instrumentation*
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / instrumentation*
  • Image Interpretation, Computer-Assisted / methods
  • Laser-Doppler Flowmetry / instrumentation*
  • Laser-Doppler Flowmetry / methods
  • Online Systems
  • Phantoms, Imaging
  • Rats
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted / instrumentation*
  • Tomography, Optical / instrumentation*
  • Tomography, Optical / methods
  • User-Computer Interface