Abstract
A wide variety of conjugates containing RIPs, of either chemical or recombinant type, have been made and tested against dangerous cells in vitro and in animal models. Many of these pre-clinical studies will be reviewed here dividing them on the basis of the target cell and the surface molecule specifically recognized.
MeSH terms
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Animals
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Antineoplastic Agents / adverse effects
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Antineoplastic Agents / immunology
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Antineoplastic Agents / pharmacology
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Antineoplastic Agents / toxicity
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Drug Evaluation, Preclinical
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Humans
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Immunotoxins / adverse effects
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Immunotoxins / immunology
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Immunotoxins / pharmacology
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Immunotoxins / toxicity*
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Proteins / adverse effects
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Proteins / immunology
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Proteins / pharmacology
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Proteins / toxicity*
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Ribosomes / drug effects
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Sensitivity and Specificity
Substances
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Antineoplastic Agents
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Immunotoxins
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Proteins