Immunotoxins and other conjugates: preparation and general characteristics

Giulio Fracasso; Giuseppe Bellisola; Deborah Castelletti; Giuseppe Tridente; Marco Colombatti

doi:10.2174/1389557043403909

Immunotoxins and other conjugates: preparation and general characteristics

Mini Rev Med Chem. 2004 Jun;4(5):545-62. doi: 10.2174/1389557043403909.

Authors

Giulio Fracasso¹, Giuseppe Bellisola, Deborah Castelletti, Giuseppe Tridente, Marco Colombatti

Affiliation

¹ Section of Immunology, Department of Pathology, University of Verona, Italy.

PMID: 15180510
DOI: 10.2174/1389557043403909

Abstract

Targeted toxins represent an invaluable tool offering a wide range of potential applications, both in experimental models and in the clinics. Here we will review several aspects related to the preparation and properties of carrier molecule-toxin heteroconjugates and fusion toxins.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Drug Carriers
Humans
Immunotoxins / chemistry*
Immunotoxins / toxicity*
Proteins / chemical synthesis
Proteins / chemistry*
Proteins / toxicity*
Ribosomes / drug effects

Substances

Drug Carriers
Immunotoxins
Proteins