Risk of malignant lymphoma associated with human herpesvirus-8: a case-control study in Spain

Br J Cancer. 2004 Jun 1;90(11):2145-8. doi: 10.1038/sj.bjc.6601858.

Abstract

No overall increased risk of lymphoma associated with antibodies to human herpesvirus-8 was found in 526 lymphomas and 599 controls (odds ratio (OR)=1.04, 95% confidence interval (CI)=0.62-1.75); significant increases were noted for 19 lymphoplasmacytic lymphomas (OR=4.47, 95% CI=1.34-14.85) and nine low-grade lymphoma/lymphoma B-cell NOS (OR=5.82, 95% CI=1.07-31.73).

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Case-Control Studies
  • DNA, Viral / analysis
  • Female
  • Herpesviridae Infections / complications*
  • Herpesvirus 8, Human / pathogenicity*
  • Humans
  • Incidence
  • Lymphoma, B-Cell / virology*
  • Male
  • Middle Aged
  • Odds Ratio
  • Polymerase Chain Reaction
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / virology*
  • Spain

Substances

  • DNA, Viral