Spatial heterogeneity is one of the important properties of oil. In this paper, the classical statistics method and the principles of geostatistics were used to study the spatial heterogeneity of soil properties on the Tibet plateau in the upper reaches of Minjiang River, and the relationship between vegetation type, landscape position and soil factors. Semivariogram analyses showed that there existed high degrees of spatial heterogeneity in soil moisture and soil nutrients. The test quadrats were assorted into three groups according to the landscape position and vegetation types, and then statistical analyses were made. The taxon results showed that different vegetation types had great effects on soil nutrients, and elevation was also an important factor influencing soil properties. A comprehensive index of soil properties showed that shrubs had the highest soil quality. The same trend of soil nutrients was found in the category of landscape positions. The soil nutrient contents decreased in the order of lower slope > upper slope > middle slope for the lower altitude hill, and lower slope > middle slope > upper slope for the high altitude hill. The results elucidated that the spatial heterogeneity of soil property was the result of the interaction between landscape factors and vegetation types.