Transpupillary thermotherapy for choroidal neovascular membrane in age related macular degeneration

Indian J Ophthalmol. 2004 Mar;52(1):45-9.

Abstract

Purpose: To evaluate the efficacy of transpupillary thermotherapy (TTT) in choroidal neovasularisation (CNVM) secondary to age related macular degeneration (AMD).

Material and methods: Retrospective, non-randomized study of 28 eyes of 28 patients with subfoveal CNVM (classic, occult or mixed) secondary to AMD.

Results: Fifteen patients (53.57%) maintained their pre-treatment vision, 2 (7.14%) patients showed improvement of more than 2 lines and 11 (39.28%) patients showed deterioration of vision by >2 lines. Angiographic and clinical regression of CNVM was noted in 19 patients (67.8%) on an average follow up of 15.32 +/- 3.31 months.

Conclusion: TTT leads to stabilisation of vision in 60% of treated eyes with CNVM due to AMD.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Choroidal Neovascularization / etiology
  • Choroidal Neovascularization / therapy*
  • Female
  • Fluorescein Angiography
  • Humans
  • Hyperthermia, Induced / methods*
  • Macular Degeneration / complications
  • Macular Degeneration / therapy*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome
  • Visual Acuity