A computational tool to simulate correlated activity in neural circuits

J Neurosci Methods. 2004 Jun 15;136(1):23-32. doi: 10.1016/j.jneumeth.2003.12.026.

Abstract

A new computational approach to study correlated neural activity is presented. Simulating Elementary Neural NEtworks for Correlation Analysis (SENNECA) is a specific-purpose simulator oriented to small circuits of realistic neurons. The model neuron that it implements can reproduce a wide scope of integrate-and-fire models by simply adjusting the parameter set. Three different distributions of SENNECA are available: an easy-to-use web-based version, a Matlab (Windows and Linux) script, and a C++ class library for low-level coding. The main features of the simulator are explained, and several examples of neural activity analysis are given to illustrate the potential of this new tool.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Brain / anatomy & histology
  • Brain / physiology
  • Computational Biology / methods*
  • Computational Biology / statistics & numerical data
  • Computer Simulation
  • Humans
  • Models, Neurological
  • Nerve Net / anatomy & histology*
  • Nerve Net / physiology*
  • Neural Networks, Computer
  • Software*