Abstract
The methanolic extract of leaves of Lippia nodiflora Linn. was tested for its anti-inflammatory and antinociceptive activities. The extract showed a significant (P < 0.001) anti-inflammatory activity comparable to phenylbutazone against carrageenin-induced paw edema in rats and a significant (P < 0.001) antinociceptive activity comparable to diclofenac sodium in acetic acid induced writhing in white albino mice.
MeSH terms
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Acetic Acid
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Analgesics / isolation & purification
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Analgesics / pharmacology*
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Animals
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Anti-Inflammatory Agents, Non-Steroidal / isolation & purification
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Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
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Carrageenan
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Diclofenac / therapeutic use
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Edema / chemically induced
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Edema / pathology
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Edema / prevention & control
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Female
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Foot / pathology
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Lippia / chemistry*
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Male
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Mice
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Pain Measurement / drug effects
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Plant Extracts / chemistry
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Plant Extracts / pharmacology
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Plant Leaves / chemistry
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Rats
Substances
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Analgesics
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Anti-Inflammatory Agents, Non-Steroidal
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Plant Extracts
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Diclofenac
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Carrageenan
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Acetic Acid