Anti-inflammatory and antinociceptive activities of Lippia nodiflora Linn

Pharmazie. 2004 Apr;59(4):329-30.

Abstract

The methanolic extract of leaves of Lippia nodiflora Linn. was tested for its anti-inflammatory and antinociceptive activities. The extract showed a significant (P < 0.001) anti-inflammatory activity comparable to phenylbutazone against carrageenin-induced paw edema in rats and a significant (P < 0.001) antinociceptive activity comparable to diclofenac sodium in acetic acid induced writhing in white albino mice.

Publication types

  • Comparative Study

MeSH terms

  • Acetic Acid
  • Analgesics / isolation & purification
  • Analgesics / pharmacology*
  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / isolation & purification
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
  • Carrageenan
  • Diclofenac / therapeutic use
  • Edema / chemically induced
  • Edema / pathology
  • Edema / prevention & control
  • Female
  • Foot / pathology
  • Lippia / chemistry*
  • Male
  • Mice
  • Pain Measurement / drug effects
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Plant Leaves / chemistry
  • Rats

Substances

  • Analgesics
  • Anti-Inflammatory Agents, Non-Steroidal
  • Plant Extracts
  • Diclofenac
  • Carrageenan
  • Acetic Acid