Objective: To summarize the findings about the influence of some xenobiotics on human reproduction, especially infertility.
Type of study: Review article.
Setting: The Department of Obstetrics and Gynecology, 1st Medical Faculty, Charles University and the General Faculty Hospital, Prague
Methods: Analysis of literature.
Results: A review about the influence of some xenobiotics on human reproduction was given. In some there is a possible negative influence on the results of in vitro fertilisation program. It is a question of hormone disruptors, some heavy metals, some organic solvents, pesticides and smoking of cigarettes.
Conclusion: In most of these xenobiotics there is direct evidence of their negative influence on reproduction and the results of in vitro fertilisation program. Therefore it is worth to continue in this evaluation.