Microarray-based expression analysis of human osteoblast-like cell response to anodized titanium surface

Biotechnol Lett. 2004 Mar;26(5):399-402. doi: 10.1023/b:bile.0000018258.58314.5c.

Abstract

An anodized surface significantly enhanced the adhesion of human osteoblast-like MG-63 cells to titanium. Using cDNA microarray analysis, five genes were differentially expressed while the rest remained unaltered. The results demonstrated that the anodized surface enhances cellular adhesion without significantly affecting the pattern of gene expression.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocompatible Materials / chemistry
  • Cell Adhesion / physiology
  • Cell Line
  • Gene Expression Regulation / physiology*
  • Humans
  • Implants, Experimental*
  • Materials Testing
  • Oligonucleotide Array Sequence Analysis / methods*
  • Osseointegration / physiology*
  • Osteoblasts / cytology*
  • Osteoblasts / physiology*
  • Porosity
  • Surface Properties
  • Titanium / chemistry*

Substances

  • Biocompatible Materials
  • titanium dioxide
  • Titanium