[Assay of thyrocalcitonin in cervical lymph node using fine-needle washings for the diagnosis of disseminated medullary thyroid carcinoma]

P A Isaev; V S Medvedev; A A Il'in; P O Rumiantsev; I V Chebotareva; P O Terent'ev; A Iu Abrosimov; B M Vtiurin; E M Parshkov; N V Severskaia; E V Marchenko

[Assay of thyrocalcitonin in cervical lymph node using fine-needle washings for the diagnosis of disseminated medullary thyroid carcinoma]

Vopr Onkol. 2004;50(1):46-9.

[Article in Russian]

Authors

P A Isaev¹, V S Medvedev, A A Il'in, P O Rumiantsev, I V Chebotareva, P O Terent'ev, A Iu Abrosimov, B M Vtiurin, E M Parshkov, N V Severskaia, E V Marchenko

Affiliation

¹ Center for Medical Radiology Research, Russian Academy of Medical Sciences, Obninsk.

PMID: 15088520

Abstract

Fine-needle aspiration biopsy of cervical lymph nodes was carried out in 22 patients with suspected metastatic involvement with medullary thyroid carcinoma (MTS). It was followed by cytopathological examination of aspirates and assay of of thyrocalcitonin (TCT) in fine-needle washings. TCT determinations proved highly informative as well as significantly high in all seven cases of MTS involvement (26-8,484.87 pg/ml, mean 2,208 +/- 1,722 pg/ml).

Publication types

English Abstract

MeSH terms

Adolescent
Adult
Biomarkers, Tumor / analysis*
Biopsy, Fine-Needle
Calcitonin / analysis*
Carcinoma, Medullary / chemistry
Carcinoma, Medullary / diagnosis*
Carcinoma, Medullary / pathology
Child
Female
Humans
Lymph Nodes / chemistry*
Lymphatic Metastasis / diagnosis
Male
Middle Aged
Neck
Thyroid Neoplasms / chemistry
Thyroid Neoplasms / diagnosis*
Thyroid Neoplasms / pathology

Substances

Biomarkers, Tumor
Calcitonin