Detection of Atopobium vaginae in postmenopausal women by cultivation-independent methods warrants further investigation

J Clin Microbiol. 2004 Apr;42(4):1829-31. doi: 10.1128/JCM.42.4.1829-1831.2004.

Abstract

We sequenced 16S rRNA genes from the vaginal swab contents of a postmenopausal woman with asymptomatic bacterial vaginosis (BV). Sequences from Atopobium vaginae were the most commonly detected. In a survey of 35 other postmenopausal women, this organism was detected in 44% with BV but not in any subjects deemed healthy.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actinobacteria / classification
  • Actinobacteria / genetics*
  • Actinobacteria / isolation & purification*
  • Adult
  • Female
  • Genes, rRNA
  • Gram-Positive Bacterial Infections / epidemiology
  • Gram-Positive Bacterial Infections / microbiology*
  • Humans
  • Middle Aged
  • Polymerase Chain Reaction
  • Postmenopause*
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA
  • Vaginosis, Bacterial / epidemiology
  • Vaginosis, Bacterial / microbiology*

Substances

  • RNA, Ribosomal, 16S