Antibiotic production by a Roseobacter clade-affiliated species from the German Wadden Sea and its antagonistic effects on indigenous isolates

Appl Environ Microbiol. 2004 Apr;70(4):2560-5. doi: 10.1128/AEM.70.4.2560-2565.2003.

Abstract

A strain affiliated with the Roseobacter clade and producing a new antibiotic named tropodithietic acid (L. Liang, Ph.D. thesis, University of Göttingen, Göttingen, Germany, 2003) was isolated from the German Wadden Sea. The compound showed strong inhibiting properties with respect to marine bacteria of various taxa and marine algae. Antibiotic production was found to occur during the complete growth phase. Strain mutants without antagonistic properties appeared several times spontaneously.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / biosynthesis*
  • Anti-Bacterial Agents / pharmacology
  • Bacteria / drug effects
  • DNA, Bacterial / genetics
  • Eukaryota / drug effects
  • Germany
  • Molecular Sequence Data
  • Phylogeny
  • Roseobacter / classification
  • Roseobacter / genetics
  • Roseobacter / isolation & purification
  • Roseobacter / metabolism*
  • Seawater / microbiology

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial

Associated data

  • GENBANK/AY208974
  • GENBANK/AY208975
  • GENBANK/AY208976
  • GENBANK/AY208977
  • GENBANK/AY208978
  • GENBANK/AY208979
  • GENBANK/AY208980