Abstract
A total synthesis following the sequence in Scheme 1 confirms that porritoxin possesses revised structure 3, not the originally assigned 1. A key reaction was the use of iron pentacarbonyl to formylate an aryllithium when DMF and methyl formate proved insufficiently reactive.
MeSH terms
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Biological Factors / chemical synthesis*
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Dimethylformamide / chemistry
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Formates / chemistry
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Formic Acid Esters / chemistry
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Indoles / chemical synthesis*
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Iron Carbonyl Compounds
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Isoindoles
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Lithium / chemistry
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Organometallic Compounds / chemistry
Substances
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Biological Factors
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Formates
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Formic Acid Esters
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Indoles
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Isoindoles
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Organometallic Compounds
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porritoxin
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formic acid
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Iron Carbonyl Compounds
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methyl formate
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Dimethylformamide
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Lithium