Cytotoxic activity of five compounds isolated from Colombian plants

Fitoterapia. 2004 Mar;75(2):225-7. doi: 10.1016/j.fitote.2003.12.017.

Abstract

Cytotoxic effect of five known compounds, khellin, berberine, lupeol, scopolin, rapanone, obtained from Colombian plants, were determined against human tumor cell lines as an indicator of the potential anticancer activity of these compounds. Berberine and rapanone presented interesting cytotoxicity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Phytogenic / administration & dosage
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Antineoplastic Agents, Phytogenic / therapeutic use
  • Benzoquinones / administration & dosage
  • Benzoquinones / pharmacology*
  • Benzoquinones / therapeutic use
  • Berberine / administration & dosage
  • Berberine / pharmacology*
  • Berberine / therapeutic use
  • Cell Line, Tumor / drug effects
  • Colombia
  • Fruit
  • HT29 Cells / drug effects
  • Humans
  • Medicine, Traditional
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Plants, Medicinal*
  • Seeds

Substances

  • Antineoplastic Agents, Phytogenic
  • Benzoquinones
  • Plant Extracts
  • Berberine
  • rapanone