Abstract
Serum samples were obtained from healthcare workers 5 weeks after exposure to an outbreak of severe acute respiratory syndrome (SARS). A sensitive dot blot enzyme-linked immunosorbent assay, complemented by a specific neutralization test, shows that only persons in whom probable SARS was diagnosed had specific antibodies and suggests that subclinical SARS is not an important feature of the disease.
MeSH terms
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Antibodies, Viral / blood
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Disease Outbreaks*
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Enzyme-Linked Immunosorbent Assay
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Health Personnel*
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Neutralization Tests
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Occupational Diseases / diagnosis
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Occupational Diseases / epidemiology*
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Occupational Diseases / immunology
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Seroepidemiologic Studies
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Severe Acute Respiratory Syndrome / diagnosis
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Severe Acute Respiratory Syndrome / epidemiology*
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Severe Acute Respiratory Syndrome / immunology*
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Severe acute respiratory syndrome-related coronavirus / immunology
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Singapore / epidemiology