Abstract
Objective:
To study the effect of TCTS on endometriosis rats.
Method:
On the model of surgical induced rat endometriosis, weight and pathological changes of endometrial transplant and serum hormones were observed.
Result:
Weight of endometrial transplants was reduced by TCTS 11.2 g.kg-1 and 22.5 g.kg-1 and transplants of TCTS treated rat showed poorly developed epithelium, thinner stroma, fewer stromal cells and glands. At the same time elevated serum E2, FSH and LH were reduced by TCTS.
Conclusion:
TCTS can inhibit the growth of endometrial transplants, which is related with serum hormone, especially E2.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cinnamomum zeylanicum / chemistry
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Curcuma / chemistry
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Drug Combinations
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Drugs, Chinese Herbal / isolation & purification
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Drugs, Chinese Herbal / pharmacology*
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Endometriosis / blood
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Endometriosis / pathology*
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Endometrium / pathology*
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Estradiol / blood
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Female
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Follicle Stimulating Hormone / blood
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Luteinizing Hormone / blood
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Phytotherapy
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Plants, Medicinal / chemistry*
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Prunella / chemistry
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Rats
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Rats, Sprague-Dawley
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Uterine Diseases / blood
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Uterine Diseases / pathology*
Substances
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Drug Combinations
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Drugs, Chinese Herbal
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Estradiol
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Luteinizing Hormone
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Follicle Stimulating Hormone