Abstract
The paper describes the properties of interleukin-18 (IL-18), the cytokine originally designated as interferon-gamma inducing factor (IGIF): its production, structure and receptor (IL-18R) transmitting a signal to the cell. Moreover, it presents recent data on its biological activity.
MeSH terms
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Animals
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Humans
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Interleukin-18 / biosynthesis
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Interleukin-18 / metabolism*
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Interleukin-18 Receptor alpha Subunit
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Receptors, Interleukin / metabolism*
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Receptors, Interleukin-18
Substances
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IL18R1 protein, human
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Interleukin-18
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Interleukin-18 Receptor alpha Subunit
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Receptors, Interleukin
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Receptors, Interleukin-18