RNA ligase; picking up the pieces

Mol Cell. 2004 Feb 27;13(4):455-6. doi: 10.1016/s1097-2765(04)00089-9.

Abstract

In the current issue of Structure, Ho and coworkers report the crystal structure and mechanism of a T4 RNA ligase. These studies provide valuable insights on the mechanism and origin of RNA and DNA ligases, and RNA capping enzymes.

Publication types

  • Review

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Crystallography, X-Ray
  • DNA Ligases / chemistry
  • DNA Ligases / metabolism
  • DNA Repair
  • Models, Biological
  • Protein Structure, Tertiary
  • RNA Caps / metabolism
  • RNA Ligase (ATP) / chemistry
  • RNA Ligase (ATP) / metabolism*
  • Viral Proteins / chemistry
  • Viral Proteins / metabolism*

Substances

  • RNA Caps
  • Viral Proteins
  • Adenosine Triphosphate
  • DNA Ligases
  • RNA Ligase (ATP)
  • bacteriophage T4 RNA ligase 2