Abstract
In the current issue of Structure, Ho and coworkers report the crystal structure and mechanism of a T4 RNA ligase. These studies provide valuable insights on the mechanism and origin of RNA and DNA ligases, and RNA capping enzymes.
MeSH terms
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Adenosine Triphosphate / metabolism
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Crystallography, X-Ray
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DNA Ligases / chemistry
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DNA Ligases / metabolism
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DNA Repair
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Models, Biological
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Protein Structure, Tertiary
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RNA Caps / metabolism
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RNA Ligase (ATP) / chemistry
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RNA Ligase (ATP) / metabolism*
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Viral Proteins / chemistry
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Viral Proteins / metabolism*
Substances
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RNA Caps
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Viral Proteins
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Adenosine Triphosphate
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DNA Ligases
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RNA Ligase (ATP)
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bacteriophage T4 RNA ligase 2