From the young to the elderly, distal radius fractures are very common. Extensive literature has been written regarding surgical management of distal radius fractures, but the same degree of attention has not been given to the critical rehabilitation that follows. Successful functional outcomes for distal radius fractures are a result of appropriate surgical treatment as well as timely and specific rehabilitation. Surgical treatment strategies available for unstable distal radius fractures include percutaneous pinning, external fixation, dorsal plating, and volar fixed-angle plating. Arthroscopically assisted as well as other minimally invasive techniques are now gaining acceptance. The ideal surgical treatment would provide stable fixed-angle fragment-specific support with minimal soft tissue disturbance and allow safe, early active wrist rehabilitation. This article reviews the normal anatomy of the region, the pathoanatomy created by the different stabilization strategies, and specific therapy techniques, including static and static progressive splints, that correlate with each of the surgical procedures.