Abstract
[structure: see text] A model system has been developed to study the synergy between aromatic stacking and hydrogen bonding in the binding of a flavin derivative. The results show that the identity of both the hydrogen bonding and pi-stacking units strongly determine the overall receptor affinity for flavin in both the oxidized and radical anion forms.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Flavin Mononucleotide / chemistry
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Flavin Mononucleotide / metabolism*
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Flavin-Adenine Dinucleotide / chemistry
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Flavin-Adenine Dinucleotide / metabolism*
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Hydrogen Bonding
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Oxidation-Reduction
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Oxidoreductases / chemistry*
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Oxidoreductases / metabolism*
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Xanthenes / chemistry
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Xanthenes / metabolism
Substances
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Xanthenes
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Flavin-Adenine Dinucleotide
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Flavin Mononucleotide
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Oxidoreductases