A pair of new C-21 steroidal glycoside epimers from the roots of Cynanchum paniculatum

Shun-Lin Li; Hua Tan; Yue-Mao Shen; Kazuyoshi Kawazoe; Xiao-Jiang Hao

doi:10.1021/np034013c

A pair of new C-21 steroidal glycoside epimers from the roots of Cynanchum paniculatum

J Nat Prod. 2004 Jan;67(1):82-4. doi: 10.1021/np034013c.

Authors

Shun-Lin Li¹, Hua Tan, Yue-Mao Shen, Kazuyoshi Kawazoe, Xiao-Jiang Hao

Affiliation

¹ State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, People's Republic of China. lisl@mail.kib.ac.cn

PMID: 14738392
DOI: 10.1021/np034013c

Abstract

Two new C-21 steroidal glycoside epimers, paniculatumosides A and B (1 and 2), based on a 13,14:14,15-disecopregnane-type skeleton, with neocynapanogenin B (3) and neocynapanogenin C (4) as two new aglycons, were isolated from the roots of Cynanchum paniculatum. Their structures were determined by spectral data interpretation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cynanchum / chemistry*
Glycosides / chemistry
Glycosides / isolation & purification*
Glycosides / pharmacology
Medicine, Chinese Traditional
Methicillin Resistance
Microbial Sensitivity Tests
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Roots / chemistry
Plants, Medicinal / chemistry*
Staphylococcus aureus / drug effects
Stereoisomerism
Steroids / chemistry
Steroids / isolation & purification*
Steroids / pharmacology

Substances

Glycosides
Steroids
neocynapanogenin B
paniculatumoside A