Cognitive training is an important aim of treatment for patients with schizophrenia. However, computer-based cognitive training is still not widely used, and there are reservations concerning the use of computers in psychiatric treatment. In a multicentre study, 64 patients with schizophrenia were investigated before and after completing a 5-week course of computer-based cognitive training using the program Cogpack. In addition to self-rating of computer anxiety (CARS) and subjective well-being (SWN), patients underwent semistructured interviews evaluating attitudes towards the training. The training was rated as highly acceptable by patients and experienced as very effective. Patients' expectations of possible training effects were largely met. The training ranked high in patients' judgement compared with other treatments received. Besides improvement in cognitive function (primary effect), patients enjoyed the training and reported increased self-esteem and progress in using computers (secondary effects). Computer anxiety scores at onset of treatment did not exceed normal values. After completion of the training, these scores were significantly reduced and subjective well-being significantly increased.