Recurrent transverse myelitis associates with anti-Ro (SSA) autoantibodies

Neurology. 2004 Jan 13;62(1):147-9. doi: 10.1212/01.wnl.0000101715.32569.1a.

Abstract

Transverse myelitis (TM) is an idiopathic inflammatory disorder of the spinal cord. The authors observed cases of recurrent TM in patients where anti-Ro (SSA) antibodies were present and therefore performed a case-control study to examine the frequency of anti-Ro autoantibodies in patients with recurrent TM and control subjects. Antibodies to 52-kd Ro were demonstrated in 77% of cases (10/13) compared with only 33% of control subjects (4/12).

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Age of Onset
  • Aged
  • Antibodies, Antinuclear / blood
  • Autoantibodies / blood*
  • Autoantigens*
  • Case-Control Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Myelitis, Transverse / diagnosis
  • Myelitis, Transverse / immunology*
  • RNA, Small Cytoplasmic*
  • Recurrence
  • Retrospective Studies
  • Ribonucleoproteins / immunology*

Substances

  • Antibodies, Antinuclear
  • Autoantibodies
  • Autoantigens
  • RNA, Small Cytoplasmic
  • RO60 protein, human
  • Ribonucleoproteins
  • SS-A antigen