Abstract
Transverse myelitis (TM) is an idiopathic inflammatory disorder of the spinal cord. The authors observed cases of recurrent TM in patients where anti-Ro (SSA) antibodies were present and therefore performed a case-control study to examine the frequency of anti-Ro autoantibodies in patients with recurrent TM and control subjects. Antibodies to 52-kd Ro were demonstrated in 77% of cases (10/13) compared with only 33% of control subjects (4/12).
MeSH terms
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Adolescent
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Adult
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Age of Onset
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Aged
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Antibodies, Antinuclear / blood
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Autoantibodies / blood*
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Autoantigens*
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Case-Control Studies
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Female
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Follow-Up Studies
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Humans
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Male
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Middle Aged
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Myelitis, Transverse / diagnosis
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Myelitis, Transverse / immunology*
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RNA, Small Cytoplasmic*
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Recurrence
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Retrospective Studies
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Ribonucleoproteins / immunology*
Substances
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Antibodies, Antinuclear
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Autoantibodies
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Autoantigens
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RNA, Small Cytoplasmic
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RO60 protein, human
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Ribonucleoproteins
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SS-A antigen