Abstract
Exposure to high-intensity light led to pronounced destructive changes in the retina and focal loss of layers formed by neurosensory cells in rats. Photoinjury led to progressive decrease in the numerical density of nuclei in the outer nuclear layer (by 30% after 2 days, by 75% after 1 week, and more than by 90% after 2 weeks of exposure). After 30 days the photosensory layer completely disappeared, while the outer nuclear layer was presented by solitary nuclei of neurosensory cells.
MeSH terms
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Animals
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Choroid / blood supply
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Choroid / radiation effects*
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Choroid / ultrastructure
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Female
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Light / adverse effects*
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Male
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Neurons / pathology
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Neurons / radiation effects
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Neurons / ultrastructure
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Pigment Epithelium of Eye / pathology
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Pigment Epithelium of Eye / radiation effects*
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Pigment Epithelium of Eye / ultrastructure
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Radiation Injuries, Experimental / pathology*
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Rats
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Retina / pathology
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Retina / radiation effects*
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Retina / ultrastructure
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Retinal Degeneration / etiology
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Retinal Degeneration / pathology*
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Time Factors