No abstract available
MeSH terms
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Animals
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Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
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Arginine / pharmacology
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Cyclic GMP / physiology*
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Cyclooxygenase 2
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Cyclooxygenase 2 Inhibitors
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Cyclooxygenase Inhibitors / pharmacology*
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Dose-Response Relationship, Drug
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Enzyme Inhibitors / pharmacology
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Female
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Guanylate Cyclase / antagonists & inhibitors
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Isoenzymes / metabolism
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Lactones / pharmacology*
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Molsidomine / analogs & derivatives*
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Molsidomine / pharmacology
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NG-Nitroarginine Methyl Ester / pharmacology
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Nitric Oxide / physiology*
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Nitric Oxide Donors / pharmacology
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Nitric Oxide Synthase / antagonists & inhibitors
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Oxadiazoles / pharmacology
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Pain / chemically induced
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Pain / drug therapy*
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Prostaglandin-Endoperoxide Synthases / metabolism
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Quinoxalines / pharmacology
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Rats
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Rats, Wistar
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Sulfones
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Uric Acid
Substances
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1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one
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Anti-Inflammatory Agents, Non-Steroidal
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Cyclooxygenase 2 Inhibitors
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Cyclooxygenase Inhibitors
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Enzyme Inhibitors
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Isoenzymes
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Lactones
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Nitric Oxide Donors
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Oxadiazoles
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Quinoxalines
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Sulfones
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rofecoxib
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Uric Acid
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Nitric Oxide
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linsidomine
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Arginine
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Molsidomine
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Nitric Oxide Synthase
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Cyclooxygenase 2
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Prostaglandin-Endoperoxide Synthases
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Guanylate Cyclase
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Cyclic GMP
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NG-Nitroarginine Methyl Ester